KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP2K3
All Species:
13.33
Human Site:
S11
Identified Species:
24.44
UniProt:
P46734
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46734
NP_002747.2
347
39318
S11
P
A
S
S
Q
P
A
S
M
P
Q
S
K
G
K
Chimpanzee
Pan troglodytes
Q9XT09
393
43428
P15
P
I
Q
L
N
P
A
P
D
G
S
A
V
N
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546666
347
39324
S11
P
A
S
S
Q
P
A
S
M
P
Q
T
K
G
K
Cat
Felis silvestris
Mouse
Mus musculus
O09110
347
39278
S11
P
A
A
S
P
P
A
S
L
P
Q
T
K
G
K
Rat
Rattus norvegicus
Q4KSH7
419
47517
P67
S
S
P
Q
H
P
T
P
P
S
R
P
R
H
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511595
352
40240
P16
E
E
M
G
F
R
S
P
R
S
R
K
L
S
R
Chicken
Gallus gallus
Q90891
398
44059
S17
P
A
L
T
I
T
P
S
P
A
E
G
P
G
P
Frog
Xenopus laevis
Q07192
446
50082
Y96
I
R
K
L
E
T
S
Y
Q
K
Q
D
L
R
T
Zebra Danio
Brachydanio rerio
Q9DGE0
361
40575
P27
P
K
G
E
M
S
V
P
S
N
V
R
G
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477162
334
38176
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20347
363
41178
M13
D
E
N
L
R
N
S
M
S
L
R
P
T
S
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJV0
356
39818
A17
Q
L
K
L
S
V
P
A
Q
E
S
P
I
S
S
Baker's Yeast
Sacchar. cerevisiae
P08018
668
72701
S307
T
G
N
S
N
N
S
S
N
S
G
S
S
G
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.7
N.A.
99.1
N.A.
96.5
37.2
N.A.
89.7
30.3
42.1
75.3
N.A.
57
N.A.
37.7
N.A.
Protein Similarity:
100
47
N.A.
99.7
N.A.
98.8
56.7
N.A.
93.1
48.7
58
84.4
N.A.
72.9
N.A.
55.6
N.A.
P-Site Identity:
100
20
N.A.
93.3
N.A.
73.3
6.6
N.A.
0
26.6
6.6
13.3
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
26.6
N.A.
100
N.A.
93.3
26.6
N.A.
20
40
20
13.3
N.A.
0
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
23.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.2
35.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
31
8
0
0
0
31
8
0
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% D
% Glu:
8
16
0
8
8
0
0
0
0
8
8
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
8
0
0
0
0
0
8
8
8
8
39
16
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
8
8
0
0
8
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
8
16
0
0
0
0
0
0
8
0
8
24
8
31
% K
% Leu:
0
8
8
31
0
0
0
0
8
8
0
0
16
0
8
% L
% Met:
0
0
8
0
8
0
0
8
16
0
0
0
0
0
8
% M
% Asn:
0
0
16
0
16
16
0
0
8
8
0
0
0
8
0
% N
% Pro:
47
0
8
0
8
39
16
31
16
24
0
24
8
0
8
% P
% Gln:
8
0
8
8
16
0
0
0
16
0
31
0
0
0
0
% Q
% Arg:
0
8
0
0
8
8
0
0
8
0
24
8
8
8
8
% R
% Ser:
8
8
16
31
8
8
31
39
16
24
16
16
8
24
8
% S
% Thr:
8
0
0
8
0
16
8
0
0
0
0
16
8
0
8
% T
% Val:
0
0
0
0
0
8
8
0
0
0
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _